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1987年2月～1991年7月,旧金山加利福尼亚大学医学院共收治84例脑瘤病人,其中成人45例,儿童39例,平均年龄24岁。病变位于脑干和丘脑者78例,其他部位6例。对这组病人中的81例进行治疗反应、复发时间和生存期的评价。放疗于诊断后4周内开始,采用大剂量高分割照射,即:每次1.0Gy(每日2次,间隔4～8小时),共78次,处方剂量78Gy。早期反应的评价是通过比较治疗前和治疗后2周内的MR和神经系统检查。后期反应的评价是
From February 1987 to July 1991, a total of 84 brain tumor patients were admitted to the University of California, San Francisco School of Medicine, including 45 adults and 39 children, with a mean age of 24 years. 78 lesions were located in the brainstem and thalamus, 6 were in other sites. Eighty-one patients in this group were evaluated for treatment response, time to recurrence, and survival. Radiotherapy began within 4 weeks after diagnosis, using high-dose high-split irradiation, namely: each 1.0Gy (twice daily, interval 4 ~ 8 hours), a total of 78 times, the prescription dose of 78Gy. Early response was evaluated by comparing MR and neurological examinations before and 2 weeks after treatment. Post-reaction evaluation is