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目的:对调强适形放疗进行阐述,探讨调强适形放疗治疗初治鼻咽癌的临床疗效,搜集相关资料和数据,为日后临床治疗初治鼻咽癌提供参考。方法:选择我院在2012年9月-2013年9月收治的130例初治鼻咽癌患者作为研究对象,按照医学上的分类方法,Ⅰ期患者共有4例,Ⅱ期患者共有18例,Ⅲ期患者共有57例,Ⅳ期患者共有51例。根据患者的患病时间长短、病理特征等,采用调强适形放疗进行临床治疗,观察临床效果,将得到的数据进行分析。结果:患者接受调强适形放疗治疗后,最严中的急性不良反应集中在放射性黏膜炎,晚期不良反应主要表现为口干。证明初治鼻咽癌患者接受调强适形放疗治疗后,临床康复明显,未来可以在临床治疗中推广应用。结论:鼻咽癌IMRT靶区剂量高,周围正常组织受量小,不良反应较轻,是一种治疗初治鼻咽癌的有效方法。另一方面,今后临床治疗,需要注意远处转移,这种情况很有可能导致治疗失败。
OBJECTIVE: To describe the intensity-modulated conformal radiotherapy and to discuss the clinical efficacy of intensity-modulated conformal radiotherapy in the treatment of nasopharyngeal carcinoma, and to collect relevant data and data to provide reference for clinical treatment of nasopharyngeal carcinoma. Methods: A total of 130 nasopharyngeal carcinoma patients treated in our hospital from September 2012 to September 2013 were selected as the research object. According to the medical classification, there were 4 cases in stage Ⅰ, 18 cases in stage Ⅱ, A total of 57 patients with stage Ⅲ, Ⅳ patients a total of 51 cases. According to the patient’s duration of illness, pathological features, etc., with intensity-modulated conformal radiotherapy for clinical treatment, observe the clinical effect, the data obtained for analysis. Results: The patients receiving intensive acupuncture and conformal radiotherapy, the most serious acute adverse reactions focused on radiation mucositis, late adverse reactions mainly manifested as dry mouth. Prove nasopharyngeal cancer patients receiving intensity-modulated conformal radiotherapy after treatment, the clinical rehabilitation obvious, the future can be applied in clinical treatment. Conclusion: IMRT nasopharyngeal carcinoma target dose is high, around the normal tissue by a small amount of adverse reactions, is an effective treatment of nasopharyngeal carcinoma. On the other hand, the future clinical treatment, need to pay attention to distant metastasis, this situation is likely to lead to treatment failure.