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先天性畸形是当前威胁儿童健康的一种主要疾病。国外报导先天性畸形的发生率估计至少为3—4％,国内报导为1—2％左右,不仅是死胎死产和约为20％围产儿死亡的主要原因,而且会给家庭和社会增加严重负担。迄今,其病因的研究多系病例的统计分析或对个别致畸因素的研究,从流行病学角度探讨各种因素对产生畸形儿影响的报导国内外均少见。1981—1982年我们作了新生儿先天性显露畸形的病例对照调查,结果如下: 一、材料与方法本次调查选定哈市妇产医院产科及我校附属第一医院产科作为科研协作单位,由有经验的专科医生负责对分娩室,婴儿室的新生儿逐一检查,按统一登记表认真记载查出的畸形儿。
Congenital malformations are one of the major diseases currently threatening children’s health. The incidence of congenital malformations reported in foreign countries is estimated to be at least 3-4% and reported at around 1-2% in the country, which is not only the main cause of stillbirths and perinatal deaths of about 20%, but also adds a serious burden to families and society . So far, the etiology of the multi-line analysis of cases or statistical analysis of individual teratogenic factors, from an epidemiological perspective of various factors on the impact of teratogenic children reports are rare at home and abroad. 1981-1982 we made congenital malformations neonatal case-control survey, the results are as follows: First, the material and methods The survey selected Harbin Obstetrics and Gynecology Hospital obstetrics and gynecology at the First Affiliated Hospital obstetrics as a research collaboration unit, from Experienced specialist is responsible for the delivery room, baby room newborn check one by one, according to a unified registration form carefully recorded out of the deformed children.