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对难治性白血病的治疗是当今血液病工作者面临的难题之一。其发生的原因主要是由于多药耐药(MDR)的存在。虽然环孢素 A(Cs A)作为 MDR逆转剂在临床上已有应用 ,但其有效性尚有待进一步证实 [1] ,其完全缓解持续的时间报道尚少。我们对 1998年 1月至 2 0 0 0年 12月收治的难治性
The treatment of refractory leukemia is one of the challenges faced by today’s hematological workers. The reason for its occurrence is mainly due to the existence of multidrug resistance (MDR). Although cyclosporin A (Cs A) has been used clinically as an MDR reversal agent, its effectiveness has yet to be further confirmed [1], and its duration of complete remission is still low. We treated refractory from January 1998 to December 2000