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目的探讨逍遥丸联合布拉氏酵母菌治疗围绝经期功能性消化不良(MPFD)的临床疗效。方法将64例MPFD患者随机分为对照组(n=30)和观察组(n=34),对照组用布拉氏酵母菌1.0g/次,2次/d,餐后服;治疗组在对照组基础上用逍遥丸8丸/次,3次/d口服,4周为1疗程。随访6个月的复发率。结果观察组显效率为47.06%,总有效率为88.23%;对照组显效率为23.33%,总有效率为66.67%。两组比较观察组明显优于对照组(P<0.05)。6个月后两组复发率比较:观察组3例(10.00%),对照组8例(40.00%),两组比较差异有统计学意义(P<0.05)。结论逍遥丸联合布拉氏酵母菌对MPFD有良好的临床疗效。
Objective To investigate the clinical efficacy of Xiaoyao Pill combined with B. Cerevisiae in the treatment of functional dyspepsia (MPFD) in perimenopausal period. Methods Sixty-four patients with MPFD were randomly divided into control group (n = 30) and observation group (n = 34). The control group was treated with Saccharomyces cerevisiae 1.0g / time, twice daily, Control group based on Xiaoyao Pill 8 pills / time, 3 times / d orally, 4 weeks for a course of treatment. The recurrence rate was followed up for 6 months. Results The effective rate of the observation group was 47.06%, the total effective rate was 88.23%; the effective rate of the control group was 23.33%, the total effective rate was 66.67%. The two groups were significantly better than the control group (P <0.05). After 6 months, the recurrence rates of the two groups were compared: 3 cases (10.00%) in the observation group and 8 cases (40.00%) in the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion Xiaoyao Pill combined with S.pastoris has a good clinical effect on MPFD.