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目的探讨小剂量肝素预防和治疗急性早幼粒细胞白血病(APL)联合化疗并发弥漫性血管内凝血(DIC)的疗效。方法对26例急性早幼粒细胞白血病患者按治疗方法分为2组,Ⅰ组为联合化疗加小剂量肝素;Ⅱ组为单用联合化疗。比较两组的 DIC 发生率和完全缓解率。结果治疗组和对照组 DIC 的发生率差异有显著性意义(P<
Objective To investigate the efficacy of low-dose heparin in preventing and treating acute promyelocytic leukemia (APL) combined with diffuse intravascular coagulation (DIC). Methods Twenty-six patients with acute promyelocytic leukemia were divided into two groups according to the treatment method. Group Ⅰ was combined with chemotherapy and low-dose heparin. Group Ⅱ was combined with chemotherapy alone. The incidence of DIC and complete remission were compared between the two groups. Results There was significant difference in the incidence of DIC between the treatment group and the control group (P <