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目的 :研制防治产后乳汁分泌不足的中药复方制剂。方法 :采用当归、黑芝麻、党参等中药 ,经水提醇沉工艺制备成养血生乳口服液 ,应用显色反应、薄层确认和高效液相色谱法控制其内在质量 ,并对 117例正常产妇进行了临床观察。结果 :正常产妇产后服用该制剂能促进产后迅速升乳 ,显著提高其日泌乳量 ,预防产后乳汁分泌不足的发生 ,并能明显促进产后子宫缩复和增强产妇免疫功能。结论 :养血生乳口服液的质量稳定 ,是防治产妇分娩后乳汁分泌不足和促进产后复旧的理想制剂。
Objective: To develop a Chinese herbal compound preparation for preventing postpartum milk secretion. METHODS: Traditional Chinese medicines such as Angelica sinensis, Black sesame and Codonopsis were prepared by water extraction and alcohol precipitation process to produce Yangxueshengji Oral Liquid. The intrinsic quality was controlled by color reaction, thin layer confirmation and high performance liquid chromatography, and 117 cases were normal. Maternal women underwent clinical observation. Results: Normal maternal postpartum administration of the preparation can promote the rapid postpartum lactation, significantly increase the daily milk production, prevent the occurrence of postpartum milk secretion, and can significantly promote postpartum uterine contraction and enhance maternal immune function. Conclusion : The quality of Yangxue Shengri Oral Liquid is stable and it is an ideal preparation for preventing maternal milk secretion after delivery and promoting postpartum oldness.