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目的探讨进展期胃癌患者采用腹腔镜辅助下胃癌根治切除术的临床效果。方法选取2014年4月—2015年9月收治的74例进展期胃癌患者,随机分为对照组和观察组各37例,对照组予以开腹根治术治疗,观察组予以腹腔镜辅助下胃癌根治术切除术治疗,并对两组患者的临床效果、不良反应发生率以及生存率情况进行对比,计量资料组间比较采用t检验,计数资料采用χ~2检验,以P<0.05为差异有统计学意义。结果观察组手术时间、术中出血量、住院时间以及胃肠道恢复时间明显少于对照组,比较差异有统计学意义(均P<0.05);观察组不良反应发生率8.10%,低于对照组的27.04%(χ~2=4.573,P<0.05);观察组生存率72.96%,低于对照组的91.89%(χ~2=4.573,P<0.05)。结论与开腹根治术相比,腹腔镜辅助下胃癌根治切除术在进展期胃癌中的应用效果显著,可使患者临床疗效显著提高,降低不良反应发生率,提高生存率。
Objective To investigate the clinical effect of laparoscopic assisted radical gastrectomy in patients with advanced gastric cancer. Methods A total of 74 patients with advanced gastric cancer who were admitted from April 2014 to September 2015 were randomly divided into control group and observation group, 37 cases in each group. The control group was treated by laparotomy and the control group was treated with laparoscopy assisted radical gastrectomy Surgical resection and treatment, and the two groups of patients with clinical effects, the incidence of adverse reactions and survival rates were compared, the measurement data were compared between groups using t test, count data usingχ ~ 2 test to P <0.05 as the difference statistics Significance of learning. Results The operation time, intraoperative blood loss, hospital stay and gastrointestinal recovery time in the observation group were significantly less than those in the control group (all P <0.05). The incidence of adverse reactions in the observation group was 8.10% (Χ ~ 2 = 4.573, P <0.05). The survival rate in the observation group was 72.96%, which was lower than 91.89% in the control group (χ ~ 2 = 4.573, P <0.05). Conclusions Compared with radical mastectomy, laparoscopic-assisted radical gastrectomy has a significant effect in advanced gastric cancer, which can significantly improve the clinical curative effect, reduce the incidence of adverse reactions and increase the survival rate.