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目的:探讨C-反应蛋白(CRP)等指标在少儿肥胖辅助诊疗中的价值。方法:少儿300例按照体重指数分为标准体重组(对照组)146例、超重组89例及肥胖组65例。采用BN-II型全自动生化分析仪对3组少儿血浆中CRP、载脂蛋白A1(Apo-A1)、载脂蛋白B(Apo-B)、白介素-6(IL-6)及纤维蛋白原等水平进行测定。结果:超重组IL-6水平显著高于对照组(P<0.05),肥胖组CRP、Apo-A1、纤维素白原和IL-6水平非常显著高于对照组(P<0.01),肥胖组CRP、Apo-A1、纤维蛋白原及IL-6水平显著高于超重组(P<0.05)。结论:肥胖少儿血浆中CRP等指标水平显著高于正常少儿,可作为少儿肥胖辅助诊疗指标。
Objective: To investigate the value of C-reactive protein (CRP) in the diagnosis and treatment of childhood obesity. Methods: Three hundred children were divided into standard body weight (control group) 146 cases, overweight group 89 cases and obesity group 65 cases according to body mass index. The plasma levels of CRP, apolipoprotein A1 (Apo-A1), apolipoprotein B (Apo-B), interleukin-6 (IL-6) and fibrinogen in children were measured by BN-II automatic biochemical analyzer. Such as the level of determination. Results: The level of IL-6 in overweight group was significantly higher than that in control group (P <0.05). The levels of CRP, Apo-A1, Cellulite and IL-6 in obesity group were significantly higher than those in control group CRP, Apo-A1, fibrinogen and IL-6 levels were significantly higher than those in overweight group (P <0.05). Conclusion: The levels of plasma CRP in obese children are significantly higher than those in normal children, which can be used as an adjunct diagnosis and treatment index for childhood obesity.