论文部分内容阅读
1目的 探讨颅内多灶性与多中心性胶质瘤的临床、病理特点及治疗方法。 2方法 对病理证实的多灶性和多中心性胶质瘤 11例进行回顾性分析 ,其中 2个病灶者 4例 ,3个病灶者 5例 ,4个病灶者和 5个病灶者各 1例 ;手术全切除 6例 ,次全切除 3例 ,活检 2例 ;行 1次手术者 5例 ,2次手术者 4例 ,3次手术者 2例 ;肿瘤局部放疗 4例 ,全脑放疗 5例。 3结果 随访 1～ 3年 ,术后生活自理 7例 ,4例需要他人照顾。 4例术后复发再入院行 2次手术。存活 1年 9例 ,2年 6例 ,3年 2例。 4结论 多灶性与多中心性胶质瘤临床上应与转移瘤鉴别 ,明确诊断对治疗方案的制订起着决定作用 ,手术力争切除肿瘤 ,术后应行全脑放射治疗
1 Objective To investigate the clinical and pathological features and treatment of intracranial multifocal and multicentric gliomas. 2 method of pathological confirmed multifocal and multicenter glioma retrospective analysis of 11 cases, including 2 lesions in 4 cases, 3 lesions in 5 cases, 4 lesions and 5 lesions in 1 case ; Surgical resection in 6 cases, subtotal resection in 3 cases and biopsy in 2 cases; 1 operation in 5 cases, 2 cases in 4 cases, 3 cases in 2 cases; tumor local radiotherapy in 4 cases, whole brain radiotherapy in 5 cases . 3 Results Follow-up 1-3 years, 7 cases of self-care after surgery, 4 cases require the care of others. 4 cases of recurrence and hospital admission 2 times surgery. 9 cases survived for 1 year, 6 cases for 2 years and 2 cases for 3 years. 4 Conclusion Multifocal and multicentric gliomas should be clinically identified with metastases, a clear diagnosis of the formulation of treatment programs play a decisive role in surgery and strive to remove the tumor, postoperative whole brain radiation therapy should be