论文部分内容阅读
为观察红色诺卡菌细胞壁骨架(Nocardiarubracellwallskeleton,N-CWS)的抑癌效应,将N-CWS皮下注射于同系移植膀胱癌小鼠并观察其抑癌效应。结果显示,给予N-CWS的小鼠存活期(23.06±5.39d)比对照组(19.06±2.75d)延长(P<0.01),存活延长率为21.0%。两组抑癌效应的观察结果显示,低荷瘤组的肿瘤消退率为4/10,而对照组无肿瘤消退,实验组平均瘤重(0.18±0.20g)明显低于对照组(4.71±1.05g),抑瘤率为96.2%(P<0.01);高荷瘤组则未观察到肿瘤消退情况,但实验组平均瘤重(3.31±0.93g)低于对照组(4.69±0.65g),抑癌率为29.4%(P<0.01)。表明N-CWS作为一种免疫促进剂具有明显的抑癌效应。
To observe the anti-cancer effect of Nocardiocyte wall scaffolding (N-CWS), N-CWS was injected subcutaneously into mice with bladder cancer and the anti-cancer effect was observed. The results showed that the survival of mice given N-CWS (23.06 ± 5.39d) was longer than that of the control group (19.06 ± 2.75d) (P <0.01), the survival rate was 21.0% . The anti-cancer effect of the two groups showed that the tumor regression rate was 4/10 in the low-tumor group and no tumor regression in the control group. The average tumor weight (0.18 ± 0.20g) in the experimental group was significantly lower than that in the control group 4.71 ± 1.05g). The tumor inhibition rate was 96.2% (P <0.01). No tumor regression was found in the high-tumor group, but the average tumor weight in the experimental group was 3.31 ± 1.05g. 93g) was lower than the control group (4.69 ± 0.65g), tumor suppression rate was 29.4% (P <0.01). It shows that N-CWS has a significant anti-cancer effect as an immunostimulant.