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我们于1975年6月底开始用本院中草药剂型改革小组所提取三尖杉有效成分一海林硷(三尖杉酯硷)及高海林硷(高三尖杉酯碱)试用于临床,用简化机率单位测得海林硷之小鼠半致死量(腹腔注射)为3.89±0.04毫克/公斤体重,高海林硷的半致死量为4.07±0.015毫克/公斤体重。50天以来,治疗了七个急性白血病病人,计海林硷四例,高海林硷三例,兹
We started in the end of June 1975 with the hospital herbal formula reform team extracted the active ingredients of Cephalotax trichosanthin (Hirshine base) and high Hailin (Homoharringtonine) trial for clinical use, with a simplified probability unit The semi-lethal dose (intraperitoneal injection) of the carnitine was 3.89 ± 0.04 mg / kg body weight, and the high lethalty alone was 4.07 ± 0.015 mg / kg body weight. Since 50 days, seven acute leukemia patients have been treated, including four cases of Hailin and three cases of Hailin.