晚发性维生素K缺乏症的临床特征及其预防

• 作 者: 朱爱华 罗敏洁 张伟利
• 机 构: 上海第二医科大学附属新华医院儿内科,上海儿童医学中心,上海市儿科医学研究所 200092
• 出 处: 临床儿科杂志
• 发表日期: 1998年06期
• 关键词: 晚发性 缺乏症 单纯母乳喂养 颅内出血 预防措施 分析基础 凝血酶原时间 凝血活酶 美国儿科学会 喂养方式

晚发性Vit K缺乏症是指生后2周～6月(2周～2月居多)婴儿因Vit K依赖因子缺乏而致出血。该病以其高颅内出血率、高死亡率和致残率而引起儿科界的关注。但在其预防对策上,国内迄今未制订出统一的常规。本文旨在通过对该病病因、临床特征等分析基础上,借鉴国外的常規预防措施,提出对所有新生儿生后常规补充Vit K以预防本病的发生。

Late onset Vit K deficiency refers to 2 to 6 months after birth (2 weeks to 2 months in most) infants due to a lack of Vit K-dependent bleeding. The disease caused by its high intracranial hemorrhage rate, high mortality and morbidity caused by the attention of the pediatric community. However, as far as its preventive measures are concerned, no unified convention has been formulated so far in the country. Based on the analysis of the etiology and clinical features of this disease, this article aims to draw lessons from the routine preventive measures abroad and propose that all newborns should be given vit Vit supplements to prevent the occurrence of this disease.