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用高效液相色谱法(HPLC)测定了大鼠心肌组织和心肌线粒体CoQ同系物的含量,并动态地分析了心肌线粒体摄取外源性CoQ_(10)后的代谢变化。结果表明,线粒体中CoQ同系物总量约占心肌全匀浆的19.49％;外源性的CoQ_(10)能够为线粒体所摄取。
The content of CoQ homologues in myocardial mitochondria and myocardial mitochondria was determined by high performance liquid chromatography (HPLC). The changes of myocardial mitochondrial metabolism of exogenous CoQ 10 were analyzed dynamically. The results showed that the total amount of CoQ homologs in mitochondria accounted for 19.49% of the total myocardial homogenate. Exogenous CoQ 10 could be taken up by mitochondria.