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目的:系统评价久坐行为与妊娠期糖尿病发病风险的相关性。方法:检索PubMed、Medline、Embase、CINAHL、Cochrane Library、The Rehabilitation & Sports Medicine Source、Sedentary Behavior Research Database、万方、中国知网和中国生物医学文献数据库中有关久坐行为与妊娠期糖尿病发病风险的队列研究、病例对照研究和横断面研究，检索时限均从建库至2021年1月23日。由2名研究员按照纳入和排除标准筛选文献、提取资料及评价质量，最后对结果进行描述性分析。结果:共纳入11篇文献，包括8项队列研究、2项横断面研究及1项病例对照研究，整体研究质量中等。妊娠期糖尿病患病率为5.04%~26.81%，妊娠期糖尿病孕妇孕前和孕期久坐行为的流行率分别为39.47%~40.21%和28.86%~93.50%。关于孕前久坐行为，有4项中等质量的研究报道与妊娠期糖尿病发病风险无关。关于孕期久坐行为，4项中等质量的研究报道与妊娠期糖尿病发病风险无关；4项研究（1项高等质量、3项中等质量）报道与妊娠期糖尿病发病风险存在正相关，其中2项研究关注妊娠中期。此外，妊娠期糖尿病和久坐行为的诊断方法研究间均存在较大异质性。结论:孕前久坐行为与妊娠期糖尿病的发病风险无关，而孕期久坐行为与妊娠期糖尿病发病风险的关系尚不明确，但妊娠中期久坐行为水平可能与妊娠期糖尿病发病风险相关。“,”Objective:To systematically evaluate the relationship between sedentary behavior (SB) and the risk of developing gestational diabetes mellitus (GDM).Methods:PubMed, Medline, EMBASE, CINAHL, the Cochrane Library, the Rehabilitation & Sports Medicine Source, the Sedentary Behavior Research Database (SBRD), Wanfang Database, the China Journal full-text database, and the China Biomedical Literature Database were searched for cohort studies, case-control studies, and cross-sectional studies concerning the risk of SB and GDM from the establishment of the database to January 2021. Two researchers screened the literature, extracted data, evaluated the quality of the data according to the inclusion and exclusion criteria, and, finally, produced a descriptive analysis of the results.Results:A total of 11 studies were included, including eight cohort studies, two cross-sectional studies, and one case-control study. The overall quality of the studies was moderate. The prevalence of GDM was 5.04%-26.81%, and the prevalence of SB before and during pregnancy was 39.47%-40.21% and 28.86%-93.50%, respectively. In terms of the prevalence of SB before pregnancy, four moderate-quality studies reported no association with GDM risk. In terms of SB during pregnancy, four moderate-quality studies reported no association with GDM risks, and four studies (one of high quality and three of moderate quality) reported an association with GDM risks, two of which focused on the second trimester. There was considerable heterogeneity between studies on the diagnosis of GDM and SB.Conclusion:SB before pregnancy is not associated with the risk of GDM, while the relationship between SB and the risk of GDM is unclear, but the level of SB in the second trimester of pregnancy may be positively associated with the risk of GDM.