超声心动图径向应变成像技术在定量分析左心室不同步及预测再同步化治疗的急性反应中的应用

• 作 者: Dohi K. Suffoletto M. S. Schwartzman D. J. Gorcsan III 姜朝晖
• 机 构: University of Pittsburgh Pittsburgh PA,United States Dr.,
• 出 处: 世界核心医学期刊文摘(心脏病学分册)
• 发表日期: 2005年11期
• 关键词: 超声心动图 急性反应 同步化 径向应变 定量分析 左心室 心脏再同步化 室间隔 再同步 技术定量

Echocardiographic strain imaging was used to quantify radial mechanical dyssynchrony in 38 patients who underwent cardiac resynchronization therapy. Dyssynchrony, defined as the time difference of peak radial strain in the septum versus the posterior wall, was significantly greater in patients with acute hemodynamic responses, and changes in radial dyssynchrony correlated with changes in stroke volume. A< 130-ms difference in septal versus posterior wall peak strain when combined with a favorable left ventricular lead position was strongly predictive of immediate improvement in stroke volume with resynchronization therapy(95%sensitivity, 88%specificity), regardless of electrocardiographic QRS duration.

Echocardiographic strain imaging was used to quantify radial mechanical dyssynchrony in 38 patients who underwent cardiac resynchronization therapy. Dyssynchrony, defined as the time difference of peak radial strain in the septum versus the posterior wall, was significantly greater in patients with acute hemodynamic responses, and changes in radial dyssynchrony correlated with changes in stroke volume. A <130-ms difference in septal versus posterior wall peak strain when combined with favorable left ventricular lead position was strongly predictive of immediate improvement in stroke volume with resynchronization therapy (95% sensitivity, 88 % specificity), regardless of electrocardiographic QRS duration.