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目的:探讨糖化血红蛋白(Hba1c)对糖尿病(DM)的诊断价值。方法:选择2011年9月—2013年2月在我院进行口服葡萄糖耐量试验(OGTT)、HbA1c检测的163例健康体检者、89例空腹血糖调节受损(IFG)患者及184例DM患者并对结果进行分析。结果:自健康体检组、IFG组至DM组,患者HbA1c及血糖水平逐渐增高,且各组件差异具有统计学意义(P<0.05);以HbA1c≥6.5%或HbA1c≥7.0%为DM诊断临界值的灵敏度及特异性均大于以FPG≥7.0mmol/L为诊断临界值。结论:HbA1c诊断DM的较血糖的灵敏度及特异性高,适合于DM早期诊断,值得推广。
Objective: To investigate the diagnostic value of glycosylated hemoglobin (Hba1c) on diabetes mellitus (DM). Methods: From September 2011 to February 2013, 163 healthy subjects undergoing oral glucose tolerance test (OGTT) and HbA1c test in our hospital, 89 patients with impaired fasting glucose regulation (IFG) and 184 DM patients Analyze the results. Results: The levels of HbA1c and blood glucose in the patients from the health examination group, the IFG group to the DM group increased gradually, and the differences among the various components were statistically significant (P <0.05). The critical value of HbA1c≥6.5% or HbA1c≥7.0% The sensitivity and specificity were greater than FPG ≥ 7.0mmol / L for the diagnostic threshold. Conclusion: The sensitivity and specificity of HbA1c in the diagnosis of DM are higher than that of blood glucose, which is suitable for early diagnosis of DM and worthy of promotion.