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异烟肼(I NH)致发作性睡病(Narcolepsy)频发,尚未见报告,1987年7月遇一例,现报告如下: 高××男 22岁住院号 50923。病人自1985年9月始,偶有睡眠延长时间至第二日中午,醒后疲乏无力,甚至到亲友家作客亦睡到下午3时,至1987年7月,就诊前两年间先后发生6~7次。此次就诊为肺结核。7月4日入院,口服I NH、RFP、肌注SM。7月14日上午9时,拍摄胸片时睡在放射线科待诊椅上、呼之不应,扶立后目瞪口呆,随即又自行躺在椅上睡去,无耐抬回病室,周身出汗,查体温、脉搏、呼吸、血压、心肺无异常。中午醒后对周围事物能理解,但不能用语言表达,片刻后恢复常态,对此事无记忆,回忆说:“听到叫自己拍片,以后就什么也不知道了”。醒后疲乏无力、头昏、无饥饿感。以后约每2~3天发病一次,有时连续2~3天发病,
There is no report on the prevalence of narcolepsy caused by isoniazid (I NH). A case was reported in July 1987 and the report is as follows: Gao XX male hospitalization number 50923, 22 years old. Patients since September 1985, the occasional sleep to extend the time to noon the second day, wake up tired and weak, and even relatives and friends to sleep also until 3 pm, to July 1987, two years prior to treatment occurred in 6 ~ 7 times. The treatment for tuberculosis. July 4 admission, oral I NH, RFP, intramuscular SM. At 9 o’clock on the July 14th, the patient who slept in the radiology department when he was shooting the chest radiograph should not sleep until he was stunned. , Check body temperature, pulse, respiration, blood pressure, no abnormal heart and lung. Noon wake up after understanding of things around, but can not use language to express, after a while back to normal, no memory of the matter, recalled: “I heard myself filming, after I do not know.” Awake after weakness, dizziness, no hunger. About every 2-3 days after the onset, sometimes 2 to 3 days of onset,