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目的 :探讨立体定向适形放疗 (Stereotactic Conformal Radiotherapy,SCRT)加肝动脉栓塞化疗 (Transcatheter Ar-terial Chemo- em bolizatina,TACE)对中晚期原发性肝癌治疗效果。方法 :对 18例中晚期原发性肝癌先予羟基喜树碱、5 - Fu、顺铂和超液化碘油行 TACE2周后行 SCRT,使用 8m v X线 ,4～ 8Gy/f,共照射 8～ 15次 ,隔日照射 ,使 90 %剂量包完 90 %的肝癌体积。结果 :全部病例均随访 18个月以上 ,6、12和 18个月的生存率分别为 72 .2 %、4 4 .4 %、2 7.8% ,其中 3例到目前仍生存。未发现严重并发症发生。结论 :中晚期原发性肝癌采用 SCRT综合 TACE能提高局部控制率 ,延长生存期 ,减轻常规分割放疗的副反应。显示出 SCRT综合 TACE对中晚期原发性肝癌的良好效果
Objective: To investigate the therapeutic effect of Stereotactic Conformal Radiotherapy (SCRT) and Transcatheter Ar-terial Chemo-em bolizatina (TACE) on advanced primary liver cancer. Methods: Eighteen patients with advanced primary hepatocellular carcinoma were treated with hydroxycamptothecin, 5 - Fu, cisplatin and lipiodol for 2 weeks and followed by SCRT for 8 ~ 8 Gy / f using 8m X ray. 15 times, irradiation every other day, so that 90% of the dose package finished 90% of liver cancer volume. Results: All the cases were followed up for more than 18 months. The survival rates at 6, 12 and 18 months were 72.2%, 44.4% and 28.8% respectively. Three of them survived till now. No serious complications were found. Conclusion: The treatment of advanced primary hepatocellular carcinoma with integrated TACE with SCRT can improve the local control rate, prolong the survival period and reduce the side effects of conventional radiotherapy. It shows the good effect of SCRT integrated TACE on advanced primary liver cancer