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对48例急性脑梗塞患者红细胞膜脂质成分及血糖、血脂、血浆脂蛋白、血尿酸等项进行测定的结果表明:急性脑梗塞组红细胞膜胆固醇、胆固醇/磷脂比值、过氧化脂质明显高于健康对照组;膜磷脂低于对照组;血糖、血脂、血尿酸正常的脑梗塞患者除膜过氧化脂质明显升高外,其余同对照组无显著性差异。直线相关分析显示:红细胞膜指质成分改变与血糖、血脂、血尿酸、血浆脂蛋白异常有显著相关性。提示急性脑梗塞患者红细胞膜脂质成分改变与严重代谢紊乱有密切关系。
In 48 patients with acute cerebral infarction, erythrocyte membrane lipid composition and blood glucose, blood lipids, plasma lipoprotein, blood uric acid and other items were measured results showed that: acute cerebral infarction group erythrocyte membrane cholesterol, cholesterol / phospholipid ratio, lipid peroxidation was significantly higher In the healthy control group, the membrane phospholipid was lower than that of the control group. There was no significant difference between the control group and the control group except the lipid peroxidation in blood glucose, blood lipids and normal blood uric acid patients. Linear correlation analysis showed that: changes in the red blood cell membrane components and blood glucose, blood lipids, serum uric acid, plasma lipoprotein abnormalities have a significant correlation. It is suggested that the change of lipid composition of erythrocyte membrane in patients with acute cerebral infarction is closely related to severe metabolic disorder.