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目的观察肝素封管液对预防PICC置管并发血栓性静脉炎的临床效果评价。方法回顾性抽取2008-2010年接受PICC置管的患者209例,均排除凝血功能障碍及血液系统疾病。实验组105例,在输液前后均用氯化钠溶液10ml行脉冲式正压冲管后再用肝素钠稀释液(浓度为10U/ml)5～10ml行脉冲式正压冲管。对照组104例,在输液前后只用氯化钠溶液冲管,方法同实验组。观察两组患者置管1个月后血栓性静脉炎的发生情况。结果实验组血栓性静脉炎的发生率明显低于对照组,两组差异具有统计学意义(P<0.01)。结论用氯化钠溶液冲管后用小剂量肝素钠稀释液封管可有效预防PICC置管期间血栓性静脉炎的发生。
Objective To observe the clinical effect of heparin sealing tube on the prevention of PICC complicated with thrombophlebitis. Methods A total of 209 patients with PICC who received catheterization during 2008-2010 were retrospectively reviewed, all of whom excluded coagulation disorders and hematologic disorders. Experimental group of 105 cases before and after infusion with sodium chloride solution 10ml positive pulse positive pulse tube after the use of heparin sodium dilute solution (concentration of 10U / ml) 5 ~ 10ml pulse positive pressure pulse tube. The control group of 104 cases, before and after infusion of sodium chloride solution only, the same method with the experimental group. The incidence of thrombophlebitis after 1 month of catheterization in both groups was observed. Results The incidence of thrombophlebitis in the experimental group was significantly lower than that in the control group, with significant difference between the two groups (P <0.01). Conclusions After pipetting with sodium chloride solution, it is effective to prevent thrombophlebitis during PICC catheterization with a small dose of heparin sodium diluent.