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目的:探讨炎琥宁联合激素丙种球蛋白治疗小儿急性原发性血小板减少性紫癜的临床疗效。方法:将我院儿科2002/2007年收治的80例小儿急性原发性血小板减少性紫癜患儿随机分成治疗组和对照组两组。两组均采用对症支持和免疫抑制治疗,治疗组在此基础上加用炎琥宁10 mg/(kg.d)治疗10 d。比较两组疗效。结果:治疗组总有效率明显高于对照组,疗效差异有统计学意义(P<0.05)。结论:炎琥宁联合激素丙种球蛋白治疗小儿原发性血小板减少性紫癜疗效肯定,值得临床推广应用。
Objective: To investigate the clinical efficacy of combined use of YSD and HgG in the treatment of children with acute primary thrombocytopenic purpura. Methods: Eighty children with acute primary thrombocytopenic purpura admitted to our hospital from 2002/2007 were randomly divided into treatment group and control group. Symptomatic support and immunosuppressive therapy were used in both groups. The treatment group was treated with melatonin 10 mg / (kg.d) for 10 days. Compare the two groups curative effect. Results: The total effective rate of the treatment group was significantly higher than that of the control group, the difference was statistically significant (P <0.05). Conclusion: Yan Hu Ning combined with hormone gamma globulin treatment of children with idiopathic thrombocytopenic purpura positive effect, worthy of clinical application.