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氨基酸是所有生物活细胞和生物体所必需的生物活性物质，其水平受到严格控制，肾脏在氨基酸代谢中发挥重要作用，包括氨基酸的合成、转运、排泄及重吸收等，其中任何一个环节出现问题都会导致体内氨基酸水平异常。氨基酸代谢异常可作为某些肾脏疾病的特征性改变，对疾病的早期诊断具有重要意义。该文就氨基酸代谢与肾脏的关系及氨基酸代谢在肾脏疾病中的作用进行综述。“,”Amino acid is a necessary for all living cells and organisms, and its level is in a state of strict regulation.The kidney plays an important role in amino acid metabolism, including amino acid synthesis, transport, excretion, and reabsorption.Dysfunction in any of these stages will cause abnormal amino acid levels in the body.Abnormal amino acid metabolism can be used as a characteristic change of certain kidney diseases, which is of great significance to the early diagnosis of the diseases.This review describes the correlation between amino acid metabolism and kidney as well as the role of amino acid metabolism in kidney diseases.