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Mogensen 等曾报告过胰岛素依赖型糖尿病患者从发病早期就见肾体积增大,且其肥大程度与肾小球滤过率相关.作者研究呈现潜在性肾病之非胰岛素依赖型糖尿病患者肾体积与尿中的蛋白排出率进展的关系,认为肾脏肥大是肾病进展的一项有用指标.观察对象为在6个月期间内至少有连续三次以上的微量蛋白尿(20～200μg/min)之非胰岛素依赖型糖尿病患者14例。其中男性9例,女性5例,平均年龄52.1±6.1岁,病程平均13.1±4.2年。
Mogensen et al reported that patients with insulin-dependent diabetes mellitus had an increased kidney volume from the early stages of onset and their degree of hypertrophy was associated with glomerular filtration rate. The authors studied the effects of kidney volume and urine in non-insulin dependent diabetic patients presenting with underlying nephropathy Renal hypertrophy is a useful indicator of progression of nephropathy.Observed non-insulin dependent microalbuminuria (20-200 μg / min) with at least three consecutive episodes over a 6-month period 14 cases of type diabetes. There were 9 males and 5 females with an average age of 52.1 ± 6.1 years and a mean duration of 13.1 ± 4.2 years.