论文部分内容阅读
目的探讨99mTc-MIBI(甲氧异腈)静息心肌灌注显像在川崎病心肌缺血及疗效评价中的临床价值。方法 41例川崎病根据病程分为急性发热期、亚急性期和恢复期3组。对照组8例系怀疑川崎病患儿,后经实验室检查排除川崎病和其他心肌疾病者。两组病例均行99mTc-MIBI静息心肌灌注显像,阳性者于治疗后6～12个月随访复查,并与其临床转归进行比较。结果对照组静息心肌灌注显像未见异常。41例川崎病患儿静息心肌灌注显像阳性率为39.02%(16/41)。其中急性期、亚急性期和恢复期患儿的阳性率分别为36.84%(7/19)、41.67%(5/12)和40%(4/10)。10例显像阳性者经治疗后6～12个月行静息心肌灌注显像复查,缺血明显改善5例,恢复正常4例,1例仍见明显心肌缺血。结论 99mTc-MIBI静息心肌灌注显像能无创、直接、客观地评价川崎病心肌缺血的部位、范围和程度,对川崎病心肌缺血的诊断和随访有一定的临床价值。
Objective To investigate the clinical value of 99mTc-MIBI myocardial ischaemia myocardial perfusion imaging in assessment of myocardial ischemia and Kawasaki disease. Methods 41 cases of Kawasaki disease were divided into acute, subacute and convalescent groups according to the course of disease. In the control group, 8 patients were suspected of Kawasaki disease and were excluded from Kawasaki disease and other myocardial diseases by laboratory tests. Resting myocardial perfusion imaging of 99mTc-MIBI was performed in both groups. The positive patients were followed up for 6-12 months after treatment and compared with their clinical outcomes. Results There was no abnormal myocardial perfusion imaging in the control group. The positive rate of resting myocardial perfusion imaging in 41 children with Kawasaki disease was 39.02% (16/41). The positive rates of acute, subacute and convalescent children were 36.84% (7/19), 41.67% (5/12) and 40% (4/10) respectively. 10 cases of positive imaging after treatment 6 to 12 months resting myocardial perfusion imaging review, significantly improved 5 cases of ischemia, returned to normal in 4 cases, 1 case still showed significant myocardial ischemia. Conclusion Resting myocardial perfusion imaging with 99mTc-MIBI can evaluate the location, extent and extent of myocardial ischemia in Kawasaki disease directly and objectively, and has some clinical value in the diagnosis and follow-up of myocardial ischemia in Kawasaki disease.