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为了探讨血清F对AFP不同浓度的原发性肝癌的诊断意义，自1993年1月至1994年12月，对243例原发性肝癌和46例健康对照组进行了血清AFP、F的检测。结果显示：原发性肝癌的血情AFP（＞400μg/L）、F（男＞250μg/L、女>150μg/L）的阳性率分别为47．7%,72．4%，与对照组比较二者差异均有高度显著性（P均＞0．01）。在AFP阴性、低浓度和阳性中F阳性率分别为73．2%（93／127）和71．6（83／116），二者比较差异无显著性（P＞0．05）。结果表明：F对原发性肝癌有诊断意义，尤其对AFP阴性、低浓度的原发性肝癌的诊断具有重要价值。
To investigate the diagnostic value of serum F in primary liver cancer with different concentrations of AFP, from January 1993 to December 1994, serum AFP and F were detected in 243 cases of primary liver cancer and 46 healthy controls. The results showed that the positive rates of AFP (>400 μg/L) and F (male>250 μg/L, female>150 μg/L) in primary liver cancer were 47.7% and 72.4%, respectively, and the control group. Comparing the two differences are highly significant (P all> 0.01). The positive rate of F positive in AFP negative, low concentration and positive was 73.2% (93/127) and 71.6 (83/116) respectively, there was no significant difference between the two (P>0.05). The results showed that F has diagnostic significance for primary liver cancer, especially for the diagnosis of AFP negative, low concentration of primary liver cancer.