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胰岛素瘤在临床上较为少见,作者通过对我院收治25 例患者的总结,进而探讨该病的定性、定位诊断及手术治疗。其中10 例患者具有 Whipple 三联征表现并因此而得到早期诊断;12 例行选择性腹腔动脉造影,10 例明确肿瘤的部位,准确率为83 % ,而B 超、CT 检查分别为16 % (4/25) ,40 % (8/20) 。25 例患者均实施手术治疗,5 例行胰体尾切除,20 例行肿瘤摘除。15 例行术中血糖监测,切除肿瘤1 小时后,血糖值均达到正常水平。因此我们认为,Whipple 三联征是胰岛素瘤定性诊断的主要依据; 选择性腹腔动脉造影对定位诊断有重要价值;诊断一旦成立,应及时手术切除肿瘤,术中血糖监测是判断肿瘤是否完全切除的有效方法。
Insulinoma is rare in clinical practice. The authors discuss the diagnosis, positioning diagnosis, and surgical treatment of the disease by summarizing the 25 patients admitted to our hospital. Among them, 10 patients had Whipple triad performance and were therefore diagnosed early; 12 patients had selective celiac artery angiography, 10 confirmed tumor sites with an accuracy of 83%, and B ultrasound and CT examination were 16% (4 /25), 40% (8/20). Twenty-five patients underwent surgical treatment. Five patients underwent pancreatic body resection and 20 patients underwent tumor removal. 15 Routine intraoperative blood glucose monitoring, after 1 hour of tumor removal, reached normal levels. Therefore, we believe that the Whipple triple syndrome is the main basis for the qualitative diagnosis of insulinoma; selective celiac artery angiography has important value in the diagnosis of localization; once the diagnosis is established, the tumor should be surgically removed. Intraoperative blood glucose monitoring is effective to determine whether the tumor is completely resected. method.