论文部分内容阅读
目的探讨中药对模拟失重导致的血循环状态紊乱的作用。方法60只大鼠随机分为4组:对照组、悬吊对照组、丹黄钙组(悬吊期间给以丹参、黄芪和碳酸钙)、参川熟组(悬吊期间给以人参、川芎和熟地),实验30天后测量各组的红细胞变形性、异形红细胞比例、血粘度、纤维蛋白原含量、红细胞聚集指数。结果与对照组比,悬吊组高、中、低切血粘度、红细胞聚集指数、纤维蛋白原含量、异形红细胞比例均明显增高,红细胞变形性明显下降。两种中药组各指标与对照组相比均无明显差别。结论两种中药合剂对模拟失重导致的血液循环状态改变有明显的防护作用。
Objective To investigate the effect of traditional Chinese medicine (TCM) on the disorder of blood circulation caused by simulated weightlessness. Methods Sixty rats were randomly divided into 4 groups: control group, suspension control group, Dan Huang calcium group (Salvia miltiorrhiza, Astragalus and calcium carbonate during suspension), Shenchuan group (given ginseng, And Rehmanniae). After 30 days of experiment, the erythrocyte deformability, the ratio of erythrocytes, blood viscosity, fibrinogen content and erythrocyte aggregation index of each group were measured. Results Compared with the control group, the hyperviscosity, middle and low shear viscosity, erythrocyte aggregation index, fibrinogen content, the proportion of abnormal red blood cells in the suspension group were significantly increased, and the deformability of erythrocytes was significantly decreased. There was no significant difference between the two TCM groups in comparison with the control group. Conclusion The two traditional Chinese medicine preparations have a significant protective effect on the changes of blood circulation caused by simulated weightlessness.