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目的:观察自拟舒天汤加氟哌噻吨美利曲辛片治疗偏头痛(气滞血瘀型)的临床疗效。方法:将60例患者随机分为2组。治疗组30例采用舒天汤配合氟哌噻吨美利曲辛片治疗,对照组30例采用氟哌噻吨美利曲辛片治疗,观察治疗前后2组患者的偏头痛总积分、临床疗效、发作期TCD颅内四条主干动脉的收缩峰值流速(Vp)和舒张末期流速(Vd)的变化。结果:治疗组治疗后的偏头痛积分优于对照组,2组比较,差异有显著性意义(P<0.05)。总有效率治疗组86.7%,对照组66.7%,2组比较,差异有显著性意义(P<0.05)。2组治疗前后TCD收缩峰值流速(Vp)、舒张末期流速(Vd)比较,差异均有显著性意义(P<0.05);2组治疗后的Vp、Vd比较,差异均有显著性意义(P<0.05)。结论:舒天汤加氟哌噻吨美利曲辛片治疗偏头痛疗效显著。
Objective: To observe the clinical efficacy of Shutian Decoction plus flupentixol and melitracen tablets in the treatment of migraine (qi stagnation and blood stasis type). Methods: Sixty patients were randomly divided into two groups. Thirty patients in the treatment group were treated with Shutiotang with flupentixol and melitracen tablets, and 30 in the control group were treated with flupentixol and melitracen tablets. The total migraine headache score and the clinical effect were observed in the two groups before and after treatment , Peak systolic velocity (Vp) and end-diastolic velocity (Vd) of the four trunk arteries in the TCD during the attack phase. Results: The scores of migraine in the treatment group were better than those in the control group. There was significant difference between the two groups (P <0.05). The total effective rate was 86.7% in the treatment group and 66.7% in the control group. There was significant difference between the two groups (P <0.05). There were significant differences in peak systolic velocity (Vp) and end-diastolic velocity (Vd) of TCD between before and after treatment in both groups (P <0.05). There were significant differences in Vp and Vd between the two groups after treatment <0.05). Conclusion: Shutian Tang plus flupentixol and melitracen tablets have significant effect on migraine.