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本文统计了我科67年1月至77年12月经病理证实的鼻咽恶性肿瘤73例,占同期放疗病人的5.5%。本组除3例外均为X线治疗,分析了临床资料和疗效,平均年龄42岁,男女之比为3:1,74%病期在一年内,平均为10.9个月,临床症状以鼻塞、头痛、耳鸣、鼻衄及颈转移最多见,45.2%有颅神经受累,颅底骨转移为24.7%。按国内分期ⅢⅣ期占85%。来本科治疗前其误诊率为16.4%。够3000拉得以上、随访满3年者59例分析疗效,3年和5年生存率分别为60%和34.6%。15例局部复发多因放疗量不足或颈部未作预防性照射,复发者经再治疗后有的治愈或延长生存期,但颅底破坏者效果不佳。早期诊断和采用高能射线治疗,探索中医中药可能是提高鼻咽癌治愈率的关键。
In this paper, 73 cases of nasopharyngeal malignancies confirmed by pathology from January 1994 to December 2007 in our department were recorded, accounting for 5.5% of patients receiving radiotherapy in the same period. In this group, X-ray treatment was used except for 3 exceptions. The clinical data and efficacy were analyzed. The average age was 42 years. The ratio of male to female was 3:1. 74% of the cases were within one year with an average of 10.9 months. The clinical symptoms were nasal congestion, Headache, tinnitus, epistaxis, and neck metastases were the most common. 45.2% had cranial nerve involvement and skull base bone metastases were 24.7%. According to the domestic phase IIIIV accounted for 85%. Before the undergraduate treatment, the misdiagnosis rate was 16.4%. The curative effect was analyzed in 59 patients who had been able to have 3,000 pull-ups and followed up for 3 years. The 3-year and 5-year survival rates were 60% and 34.6%, respectively. 15 cases of local recurrence due to lack of radiation or lack of prophylactic irradiation on the neck, recurrences were cured or prolonged survival after retreatment, but the effect of skull base destruction was poor. Early diagnosis and the use of high-energy radiation therapy to explore Chinese medicine may be the key to improve the cure rate of nasopharyngeal carcinoma.