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目的 探讨老年患者肾移植的特点及年龄增长对移植效果的影响。 方法 回顾性分析了４６例老年尿毒症患者施行肾移植的临床资料，３９ 例行肾动脉与髂外动脉端－侧吻合，７ 例肾动脉与髂内动脉端－端吻合。移植后应用环孢素Ａ、硫唑嘌呤和泼尼松三联免疫抑制药物，环孢素Ａ延迟应用，用量低于非老年患者。 结果 １年人肾存活率为８７．５％ ，３ 年存活率７１．４％ ，５ 例存活超过５年，２ 例超过１０年；仅３例发生急性排异反应，２例发生慢性排异反应。３４ 例（７３．９％ ）发生并发症。 结论 并发症是影响老年患者肾移植效果的主要因素，受者年龄与肾移植效果无直接关系。若能注意老年患者肾移植的特点，术前充分准备，移植后合理用药，积极防治并发症，能收到与非老年患者相同的移植效果
Objective To investigate the characteristics of renal transplantation in elderly patients and the effect of aging on the effect of transplantation. Methods The clinical data of 46 cases of elderly uremic patients undergoing kidney transplantation were retrospectively analyzed. The end - to - side anastomosis of renal arteries and external iliac arteries was performed in 39 cases and the end - to - end anastomosis of 7 cases of renal arteries and internal iliac arteries. Cyclosporine A, azathioprine and prednisone triple immunosuppressive drugs after transplantation, cyclosporine A delay in the application, the amount of less than non-elderly patients. Results The one-year survival rate of human kidney was 87.5%, and the three-year survival rate was 71.4%. Five patients survived for more than 5 years and two patients were over 10 years. Only 3 patients had acute rejection and 2 patients had chronic rejection reaction. Complications occurred in 34 cases (73.9%). Conclusions Complications are the main factors that affect the effect of renal transplantation in elderly patients. There is no direct relationship between the recipients’ age and the effect of renal transplantation. If we can pay attention to the characteristics of elderly patients with renal transplantation, adequate preoperative preparation, rational use of drugs after transplantation, and actively prevent complications, can receive the same transplant effect with non-elderly patients