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目的观察干扰素联合炎琥宁治疗小儿手足口病的临床应用,评价其治疗效果。方法选取该院2016年2月—2017年3月收治的小儿手足口病92例为研究对象,按照患儿入院顺序分为对照组与观察组各46例,给予对照组患儿常规治疗,所有患儿入院均行常规治疗,在此基础上对照组给予单用炎琥宁治疗,观察组给予干扰素联合炎琥宁治疗,比较两组治疗情况。结果经治疗后数据统计显示,观察组治疗总有效率91.30%(42/46)明显高于对照组71.74%(33/46),且观察组患儿症状改善时间、疱疹消退时间、住院时间、口腔溃疡愈合时间均明显由于对照组(P<0.05)。结论干扰素联合炎琥宁在治疗小儿手足口病中可达到较好临床效果,有效减少患儿住院时间与症状、体征改善时间,安全性更高,具有临床应用价值。
Objective To observe the clinical application of interferon combined with metronidazole in the treatment of hand-foot-mouth disease in children, and to evaluate its therapeutic effect. Methods A total of 92 children with HFMD in our hospital from February 2016 to March 2017 were selected as study subjects and divided into control group and observation group according to admission sequence of 46 patients, Children admitted to hospital underwent routine treatment, on the basis of the control group given single treatment of Yan Hu Ning, the observation group given interferon combined with Yan Hu Ning treatment, the two groups were compared. Results After treatment, the data showed that the total effective rate in the observation group was 91.30% (42/46), significantly higher than that in the control group (71.74%, 33/46), and the symptom improvement time, herpes regression time, length of hospital stay, Oral ulcer healing time were significantly due to the control group (P <0.05). Conclusion Interferon and mesylate can achieve better clinical results in the treatment of hand, foot and mouth disease in children, reduce the hospitalization time and symptoms, improve the time of symptom improvement and have higher safety, and have clinical value.