论文部分内容阅读
目的:为了了解20年前Hp有无感染以及感染率和感染与胃粘膜病变的关系,再结合20年后感染情况的比较,为进一步研究Hp与胃粘膜病变提供依据。方法:将1973年563例胃镜活检材料与同期1992年500例胃镜活检材料进行回顾性病理切片的阅读,记录Hp感染情况及胃粘膜病变,然后进行对比分析。结果:1973年胃粘膜活检中Hp感染率为71.0％,1992年为67.2 ％,两者几乎相等。说明在1986年以后才认识到的Hp感染早在20年前已普遍存在。进一步对慢性浅表性胃炎、慢性萎缩性胃炎、胃溃疡、十二指肠球溃疡、胃癌5种主要胃粘膜病变中Hp感染率20年前后比较亦无大的变化。结论:胃粘膜感染Hp是一个历史长久的问题,可能会追溯到古代,因此,对Hp与胃粘膜病变的内在关系要进行深入的研究,只凭短期内的材料就做出Hp与胃炎、胃癌有关的结论应取慎重态度的。
Objective: In order to understand whether there is infection of Hp 20 years ago and the relationship between infection rate and infection and gastric mucosal lesions, combined with the comparison of the infection after 20 years, provide a basis for further study of Hp and gastric mucosal lesions. Methods: 563 cases of gastroscopic biopsy material in 1973 and 500 cases of endoscopic biopsy material in 1992 were retrospectively reviewed. Hp infection and gastric mucosal lesions were recorded and compared. Results: The incidence of Hp infection in gastric mucosal biopsy was 71.0% in 1973 and 67.2% in 1992, which were almost the same. This shows that Hp infection, which was not realized after 1986, has been prevalent 20 years ago. Furthermore, no significant change was observed in Hp infection rates in five major gastric mucosal lesions of chronic superficial gastritis, chronic atrophic gastritis, gastric ulcer, duodenal ulcer, and gastric cancer over 20 years ago. Conclusion: Gastric mucosal infection of Hp is a long-standing problem that may be traced back to the ancient times. Therefore, we should conduct an in-depth study on the relationship between Hp and gastric mucosal lesions. Hp, gastritis, gastric cancer Relevant conclusions should be taken with a cautious attitude.