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目的:探讨我院药品不良反应(ADR)发生的特点与一般规律。方法:对我院ADR监测中心2007年收集到的有效报告314例进行统计、分析。结果:314例ADR报告中,涉及药品13类178种,共338例/次。主要为抗感染药(38种,128例/次)和中药制剂(20种,51例/次)。ADR累及的器官或系统中皮肤及其附件损害最多(134例/次),消化道损害居第2位(56例/次)。转归较好,仅1例死亡。结论:加强合理用药监测,可避免和减少ADR的发生。
Objective: To investigate the characteristics and general rules of adverse drug reaction (ADR) in our hospital. Methods: 314 cases of effective reports collected by ADR monitoring center in our hospital were statistically analyzed. Results: Of the 314 ADR cases, there were 178 drugs in 13 categories involving 338 cases / time. Mainly anti-infectives (38 species, 128 cases / times) and traditional Chinese medicine preparations (20 kinds, 51 cases / times). The organs and systems involved in ADR had the highest number of skin lesions and their appendages (134 cases / time) and the second group of gastrointestinal lesions (56 cases / time). Good outcome, only 1 death. Conclusion: To strengthen the rational drug use monitoring can avoid and reduce the occurrence of ADR.