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目的:通过分析青海省10年以来出生缺陷的变化趋势,探讨今后的工作重点。方法:按全国监测方案进行监测,对青海省近10年来出生缺陷监测结果进行分析。结果:共监测围产儿138 404例,监测出出生缺陷儿1 390例,围产儿出生缺陷发生率平均为100.43/万;全省出生缺陷发生率忽高忽低有所不同;青海省高发的前五位畸形是神经管畸形,总唇裂,脑积水,多指(趾),肢体短缩。10年来出生缺陷发生率呈现农村高于城市,男性围产儿高于女性围产儿。结论:对于青海省各种高发畸形进行深入的病因学研究,提高出生缺陷的产前诊断及产前筛查提出干预措施,做好出生缺陷的三级预防。
Objective: To analyze the changing tendency of birth defects in Qinghai Province in the past 10 years and to discuss the key points in the future. Methods: According to the national monitoring plan, the monitoring results of birth defects in Qinghai Province in the past 10 years were analyzed. Results: A total of 138,404 cases of perinatal children were monitored, 1,390 cases of birth defects were detected, and the average incidence of perinatal birth defects was 100.43 / million. The incidence of birth defects in the province varied from high to low; Five deformities are neural tube defects, total cleft lip, hydrocephalus, multiple fingers (toe), limb shortening. The incidence of birth defects in rural areas over the past 10 years showed higher than the perinatal children than the female perinatal children. CONCLUSIONS: In-depth etiological studies on various high-incidence deformities in Qinghai Province were conducted to improve prenatal diagnosis of birth defects and prenatal screening and to provide interventions for tertiary prevention of birth defects.