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喉乳头状瘤通常分为多发的青年型和单发的成人型二型。电子显微镜和组织学检查提示喉乳头状瘤病毒与青年型者发病有关,并从喉乳头状瘤标本鉴定出一种新型人类乳头状瘤病毒DNA(HPV 11型)。此病毒偶可见于成人,以高频度复发为其特点。由自发性或医原性散播,可侵入威胁生命、难以治疗的气管或支气管部位。本病治疗通常是用支气管镜下摘除及激光等,常需气管切开。白细胞干扰素治疗青年型喉乳头状瘤病已有报道,治疗后肿瘤缩小,但停药后复发。报告者概未作分子生物学监测。(本刊1983,7:228,文摘号234、235) 作者们报告1例54岁男性气管支气管乳头状瘤病。定期从支气管镜内摘除复发的气管乳头状瘤已有23年。6年前,乳头状瘤病发展至右肺上
Laryngeal papilloma usually divided into multiple youth-type and single adult type II. Electron microscopy and histological examination suggested that the laryngeal papilloma virus was associated with the onset of disease in young people and that a new human papillomavirus DNA (HPV type 11) was identified from specimens of laryngeal papilloma. This virus is even found in adults, with high frequency of recurrence for its characteristics. Spoiled spontaneously or medically, can invade life-threatening, intractable tracheal or bronchial parts. The disease is usually treated with bronchoscopy and laser removal, etc., often require tracheotomy. Interferon treatment of young laryngeal papillomatosis has been reported, the tumor shrinks after treatment, but relapse after stopping. The reporter did not make molecular biology surveillance. (Journal 1983,7: 228, Abstract 234, 235) The authors report a 54-year-old man with tracheobronchial disease. It has been 23 years since regular removal of recurrent tracheal papilloma from a bronchoscope. Six years ago, papilloma developed to the right lung