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目的:评价盐酸左氧氟沙星注射液对盆腔炎患者的临床疗效及安全性。方法:选取2014年3月—2015年3月间医院收治的盆腔炎患者120例,将其分为观察组和对照组(每组60例);观察组患者给予盐酸左氧氟沙星注射液治疗,对照组患者给予氧氟沙星注射液治疗,比较两组患者职后的临床疗效、腹痛缓解时间、白细胞计数复常时间、妇检复常时间和不良反应的发生情况等。结果:观察组患者治疗后总有效率为95.00%,显著高于对照组为80.00%(P<0.05);观察组患者的腹痛缓解时间为(3.21±0.52)d、白细胞计数恢复正常时间为(1.14±0.16)d和妇检恢复正常时间为(3.59±1.45)d,优于对照组腹痛缓解时间为(5.37±1.23)d、白细胞计数恢复正常时间为(2.68±1.38)d和妇检恢复正常时间(6.07±1.53)d(P<0.05);观察组患者不良反应的发生率为8.33%,低于对照组为26.67%(P<0.05)。结论:盐酸左氧氟沙星注射液治疗盆腔炎患者的临床疗效优于氧氟沙星,且不良反应发生少,安全性好。
Objective: To evaluate the clinical efficacy and safety of levofloxacin injection in patients with pelvic inflammatory disease. Methods: A total of 120 pelvic inflammatory disease patients admitted to the hospital from March 2014 to March 2015 were selected and divided into observation group and control group (60 cases in each group). Patients in observation group were treated with levofloxacin hydrochloride injection and control group Patients were treated with ofloxacin injection, clinical efficacy, postoperative abdominal pain relief time, leukocyte count time, maternal seizure time and adverse reactions were compared between the two groups. Results: The total effective rate of observation group was 95.00%, which was significantly higher than that of control group (80.00%, P <0.05). The relief time of abdominal pain in observation group was (3.21 ± 0.52) d, the recovery time of white blood cell count was ( 1.14 ± 0.16) d and maternal examination (3.59 ± 1.45) d, which was better than that of the control group (5.37 ± 1.23) d, and the leukocyte count returned to normal (2.68 ± 1.38) d (6.07 ± 1.53) d (P <0.05). The incidence of adverse reactions in the observation group was 8.33%, which was lower than that in the control group (26.67%, P <0.05). Conclusion: Levofloxacin hydrochloride injection is superior to ofloxacin in the treatment of patients with pelvic inflammatory disease, with fewer adverse reactions and good safety.