Paeonol inhibits NLRP3 mediated inflammatory reaction in rat endothelial cells by elevating hyperlip

• 作 者: SHI Xiao-yan XIE Xian-mei DAI
• 机 构: SchoolofPharmacy,KeyLaboratoryofXin′anMedicine
• 出 处: 中国药理学与毒理学杂志
• 发表日期: 2019年9期
• 关键词: PAEONOL HYPERLIPIDEMIA EXOSOMES miR-223 NLRP3 RAECs
• 基金项目: National Natural Science Foundation of China(81473386,81773937).

OBJECTIVE Atherosclerosis(AS)is featured as a chronic inflammatory disease of vascular stenosis.Paeonol(Pae)is a natural phenolic compounds isolated from a traditional Chinese medicine,Cortex Moutan,which exhibits anti-AS effects in vitro and in vivo.In t