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Norwalk因子是一种27毫微米大小的病毒样因子,见于非细菌性急性胃肠炎患者粪便滤液中,口服后可引起近段小肠病变、碳水化合物和脂肪吸收障碍。本文报告用Norwalk因子攻击和再攻击后的临床表现、小肠活检改变和血清反应的研究结果。 12名“志愿者”,于接受Norwalk因子攻击后的27～42个月后,再接受第二次攻击。结果有6名于接受第一次攻击后发病,6名不发病。在接受第二次
The Norwalk factor is a 27-nanometer virus-like factor found in the fecal filtrate of patients with non-bacterial acute gastroenteritis that causes proximal intestinal lesions, carbohydrate and fat absorption disorders after oral administration. This article reports the results of Norwalk factor challenge and re-attack clinical presentation, small intestinal biopsy and serological response. Twelve volunteers received a second attack 27 to 42 months after receiving the Norwalk factor attack. Six patients developed the disease after receiving the first attack and six did not. Accept the second time