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目的观察手术+微波+干扰素综合疗法治疗外耳道乳头状瘤的临床效果。方法对2008年1月-2011年6月收治的53例外耳道乳头状瘤患者,采用手术切除肿瘤组织,接着微波单极探头烧灼创面充分止血,然后改用微波双极探头平复创面,最后用注射器抽取重组人干扰素α-2b 100万U+0.9%生理盐水1ml溶解后作乳头状瘤基底部及其周围局部浸润注射,对广基肿瘤可采用多点注射,5d后可重复注射,共2-4次。红霉素眼膏涂于创面,常规口服抗生素1周。合并有感染者应控制感染后再治疗瘤体。术后随访6月-l年,观察肿瘤复发情况及听力。结果所有病例接受综合治疗后随访6月-l年,仅有2例复发,治愈率达96.2%。2例复发病例再次接受上述综合治疗,随访6月,最后痊愈。无1例外耳道狭窄发生。结论手术+微波+干扰素综合疗法治疗外耳道乳头状瘤,具有效果好、创伤小、复发率低、并发症少、操作简单等优点,值得临床推广使用。
Objective To observe the clinical effect of combined surgery + microwave + interferon therapy on external auditory canal papilloma. Methods 53 patients with external auditory canal papilloma admitted from January 2008 to June 2011 were treated with surgical resection of the tumor tissue, followed by a microwave unipolar probe to fully hemostat the wound surface, and then the microwave bipolar probe was used to smooth the wound. Finally, a syringe Extraction of recombinant human interferon α-2b 1 million U + 0.9% saline 1ml dissolved after the papilloma and its surrounding infiltration of the basal infiltration of wide-based tumors can be injected by injection, 5d after repeated injections, a total of 2 -4 times. Erythromycin eye ointment applied to the wound, conventional oral antibiotics for 1 week. Infection with infection should be controlled after treatment of the tumor. Postoperative follow-up 6 months-l years, observation of tumor recurrence and hearing. Results All patients were followed up for 6 months after treatment. Only 2 patients relapsed, the cure rate reached 96.2%. 2 cases of recurrent patients again accepted the above comprehensive treatment, followed up for 6 months, finally recovered. No exception occurred in the ear canal narrowing. Conclusions Surgical + microwave + interferon combined therapy for external auditory canal of the external auditory canal has the advantages of good effect, small trauma, low recurrence rate, few complications and simple operation, which is worthy of clinical promotion.