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自1989年以来我院应用雷公藤配合小剂量强的松治疗肾病综合征取得较好疗效,现总结分析如下。临床资料雷公藤加强的松治疗肾病综合征(下称治疗组)共52例,均符合全国第二届肾脏疾病学术会议关于原发性肾病综合征的诊断标准,其中肾病综合征Ⅰ型34例,Ⅱ型18例;年龄13~61岁,平均年龄33岁;男性31例,女性21例,入院时病程最短13天,最长达9年。另以1986年以来应用强的松及(或)环磷酰胺治疗的病例共53例为对照组,经比较其性别、年龄、分型及病程与治疗组在统计学上无显著差别。治疗方法一、治疗组雷公藤片(上海中药制药二厂生产,批号:沪卫药准字[1989]第148号——[中二],该品为去皮雷公藤根的浸膏片,每片含雷公藤干浸膏125mg),每次5~7片,每日2次,共治疗18例;雷公藤
Since 1989, our hospital application of triptolide with small doses of prednisone treatment of nephrotic syndrome and achieved good results, are summarized as follows. Clinical data Tripterygium enhanced pine treatment of nephrotic syndrome (hereinafter referred to as the treatment group) a total of 52 cases, are in line with the Second National Symposium on Kidney Disease on the diagnosis of primary nephrotic syndrome, including nephrotic syndrome type 34 cases , Type Ⅱ 18 cases; aged 13 to 61 years, mean age 33 years; 31 males and 21 females, the shortest duration of admission 13 days, up to 9 years. The other 53 patients treated with prednisone and / or cyclophosphamide since 1986 as the control group, no significant difference in gender, age, type and duration of treatment compared with the treatment group. Treatment method First, the treatment group Tripterygium tablets (Shanghai Traditional Chinese Medicine Factory 2 production, batch number: Shanghai Wei medicine quasi-word [1989] No. 148 - [in two], the goods for the skin Peel Tripterygium root extract tablets, each Tablets containing Tripterygium dry extract 125mg), each 5 to 7 tablets, 2 times a day, a total of 18 cases of treatment; Tripterygium