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目的了解高校教职工人群脂肪肝患病分布趋势,探讨其相关危险因素,为高校群体脂肪肝的防治工作提供一定依据。方法对2014年某高校健康体检的1 447名教职工进行身高、体重、血压、血脂、空腹血糖、转氨酶、肌酐、尿酸及腹部B超检查,并对体检结果进行分析。结果脂肪肝总检出率为25.7%,60岁之前检出率随年龄增大而增高(χ2=41.053,P<0.001),50~60岁组达高峰为37.4%,随后下降;男性检出率(38.5%)明显高于女性检出率(16.0%)(χ2=93.428,P<0.001);脂肪肝组超重肥胖、血脂紊乱、高血糖、高血压和肝功能异常检出率高于非脂肪肝组(P<0.01);超重肥胖、血脂紊乱、高血糖、高血压的检出率与脂肪肝检出率性别和年龄趋势一致,男性高于女性,与年龄呈正相关;体重指数、空腹血糖和甘油三酯分层分析,脂肪肝检出率随体重指数和甘油三酯水平增高而升高,最高达85.5%和62.0%,趋势性卡方检验χ2值为364.493和208.155(P<0.001),提示体重指数和甘油三酯与脂肪肝发生关系最为密切。结论高校教职工脂肪肝患病率高,肥胖、血脂紊乱与脂肪肝密切相关。
Objective To understand the distribution trend of fatty liver disease among university faculty workers and to explore the related risk factors so as to provide some evidences for the prevention and treatment of fatty liver in college population. Methods The height, weight, blood pressure, blood lipids, fasting blood glucose, aminotransferase, creatinine, uric acid and abdominal ultrasonography of 1,447 faculty members in a university physical examination in 2014 were analyzed. The physical examination results were analyzed. Results The total detection rate of fatty liver was 25.7%. The detection rate before 60 years old increased with age (χ2 = 41.053, P <0.001), and reached the peak of 37.4% in 50-60 years old group (38.5%) was significantly higher than that of females (χ2 = 93.428, P <0.001). The prevalence of overweight and obesity, dyslipidemia, hyperglycemia, hypertension and liver dysfunction in steatohepatitis group was higher than that in females Fatty liver group (P <0.01). The detection rate of overweight and obesity, dyslipidemia, hyperglycemia and hypertension were consistent with the detection rate of fatty liver. The male and female were higher than those of female and positively correlated with age. The body mass index, fasting Stratified analysis of blood glucose and triglycerides showed that the detection rate of fatty liver increased with body mass index and triglyceride levels up to 85.5% and 62.0%, respectively. The trend chi square test χ2 values were 364.493 and 208.155 (P <0.001) ), Suggesting that body mass index and triglyceride with fatty liver most closely. Conclusion The prevalence of fatty liver in higher education faculty is very high. Obesity and dyslipidemia are closely related to fatty liver.