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目的观察中药联合醋酸泼尼松片治疗老年慢性免疫性血小板减少症(ITP)患者的临床效果。方法将90例老年慢性ITP患者通过双色球随机分组法分为观察组(n=45)及对照组(n=45)。对照组患者采用醋酸泼尼松片治疗,结合病情合理调整剂量;观察组患者采用中药联合醋酸泼尼松片治疗。对比2组患者临床治疗效果、不良反应和复发率。结果治疗3个月、6个月后,观察组患者治疗有效率均高于对照组(P<0.05)。2组均无明显不良反应发生。观察组复发率低于对照组(P<0.05)。结论针对老年慢性ITP患者,采用中药联合醋酸泼尼松片治疗,可明显改善临床症状,降低复发率,不良反应少,临床疗效安全显著,值得推广和应用。
Objective To observe the clinical effect of traditional Chinese medicine combined with prednisone acetate in the treatment of elderly patients with chronic thrombocytopenia (ITP). Methods 90 elderly patients with chronic ITP were divided into observation group (n = 45) and control group (n = 45) by bicolor ball randomization method. The control group patients treated with prednisone acetate tablets, combined with reasonable adjustment of the dose; patients in the observation group were treated with Chinese medicine combined with prednisone acetate tablets. The clinical efficacy, adverse reactions and relapse rate in two groups were compared. Results After 3 months and 6 months of treatment, the treatment effective rate in observation group was higher than that in control group (P <0.05). No significant adverse reactions occurred in both groups. The recurrence rate of the observation group was lower than that of the control group (P <0.05). Conclusion For elderly patients with chronic ITP, using traditional Chinese medicine combined with prednisone acetate tablets can significantly improve the clinical symptoms, reduce the recurrence rate, fewer adverse reactions, the clinical efficacy of safe and worthy of promotion and application.