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镇痛新(Pentazocine)是麻醉镇痛剂phenazocine的正烯丙基衍生物,其结构式为:PhenazocineR=CH_2CH_2C_6H_5(?)PentazocmeR=CH_2CH:C(CH_3)_2 临床试用评价:广泛临床试用结果表明,镇痛新口服或注射对外科手术及内科疾病所致之中度或剧烈疼痛有效。对于大多数手术后的病例,30毫克肌肉注射即足以减轻中度及重度疼痛,但在有些研究中,约有1/5的病例却需要较高的剂量(45～60毫克)才获止痛效果。对包括1000例手术后疼痛的患者的研究表明,肌肉注射镇痛新27毫克的最大镇痛
Pentazocine is the n-allyl derivative of the narcotic analgesic phenazocine and has the following structural formula: Phenazocine R = CH 2 CH 2 C 6 H 5 (?) Pentazocme R = CH 2 CH: C (CH 3) 2 Clinical trial evaluation: Extensive clinical trial results show that the town New oral pain or injection is effective in moderate or severe pain due to surgical and medical conditions. For most post-operative cases, intramuscular injection of 30 mg is sufficient to reduce moderate and severe pain, but in some studies approximately one-fifth of cases require higher doses (45-60 mg) for analgesia . A study of 1,000 patients with post-operative pain, including intramuscular analgesia, showed a maximum of 27 mg of maximal analgesia