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目的:评价静脉用免疫球蛋白(IVIG)或复方甘草酸苷(GL)对常规治疗无效的小儿腹型过敏性紫癜(AHSP)的效果。方法:选取我院2013年1月至2016年1月收治的常规治疗7 d无缓解的55例以剧烈腹痛为主要表现的AHSP患儿,随机分为观察组29例和对照组26例。观察组给予IVIG;对照组患儿给予GL,观察治疗前后两组患儿临床症状变化情况。结果:治疗后,观察组患儿紫癜、腹痛恢复时间与对照组比较差异均无统计学意义(P>0.05)。结论:IVIG和GL治疗小儿AHSP均疗效显著,值得在临床推广应用。
Objective: To evaluate the effect of intravenous immunoglobulin (IVIG) or compound glycyrrhizin (GL) on children with atypically idiopathic purpura (AHSP) ineffectively treated. Methods: Fifty-five AHSP patients with severe abdominal pain as the main manifestation in our hospital from January 2013 to January 2016 were randomly divided into observation group (n = 29) and control group (n = 26). The observation group was given IVIG; the control group was given GL, and the changes of clinical symptoms in both groups before and after treatment were observed. Results: After treatment, purpura in children in observation group, abdominal pain recovery time compared with the control group, no significant difference (P> 0.05). Conclusion: The therapeutic effects of IVIG and GL on children with AHSP are significant and worthy of clinical application.