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目的总结复发性念珠菌外阴阴道炎的临床诊治效果,为临床提供参考。方法 100例复发性念珠菌外阴阴道炎患者,随机分为对照组和观察组,每组50例。对照组接受硝酸咪康唑栓治疗,观察组接受氟康唑联合硝酸咪康唑栓治疗。对两组接受治疗后的治疗效果进行对比分析。结果入组时两组瘙痒症状评分、白带症状评分及症状总积分比较,差异无统计学意义(P>0.05),而在治疗2周后,观察组瘙痒症状评分、白带症状评分及症状总积分显著低于对照组(P<0.05)。且观察组治疗2周后的总有效率明显高于对照组(P<0.05);两组并发症发生率比较差异无统计学意义(P>0.05)。结论采用氟康唑联合硝酸咪康唑栓治疗复发性念珠菌外阴阴道炎,可有效的提高临床治疗效果,临床可推广应用。
Objective To summarize the clinical diagnosis and treatment of recurrent candidal vulvovaginitis and provide reference for clinical practice. Methods 100 patients with recurrent Candida vulvovitis were randomly divided into control group and observation group, 50 cases in each group. The control group received miconazole nitrate suppositories, and the observation group received fluconazole plus miconazole nitrate suppositories. The treatment effect of two groups after treatment was compared and analyzed. Results The scores of pruritus symptom scores, leucorrhea symptom scores and symptom scores were not significantly different between the two groups (P> 0.05). After 2 weeks of treatment, the scores of pruritus symptom score, leucorrhea symptom score and symptom score Significantly lower than the control group (P <0.05). The total effective rate in the observation group after 2 weeks of treatment was significantly higher than that in the control group (P <0.05). There was no significant difference in the incidence of complications between the two groups (P> 0.05). Conclusion The use of fluconazole combined with miconazole nitrate suppositories in the treatment of recurrent Candida vulvovaginitis can effectively improve the clinical effect and can be extended to clinical application.