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目的探讨老年原发性高血压(EH)患者左心室肥厚(LVH)与脉压(PP)的相关性。方法测定98例原发性高血压患者收缩N(SBP)、舒张压(DBP)、PP及超声心动图的各种参数,并根据有无LVH分为两组:非LVH组42例,LVH组56例。其中LVH组伴心功能不全者26例,心功能正常者30例。结果 (1)LVH组的SBP、PP明显大于非LVH组(P<0．01);LVMI与SBP、PP呈正相关(P<0．01)。(2)LVH组伴心功能不全者PP高于LVH组心功能正常者(P<0．05)。结论 PP 增大在EH伴LVH发展中起作用,PP可作为评价抗高血压药物能否更好地减少患者靶器官损害的重要指标。
Objective To investigate the correlation between left ventricular hypertrophy (LVH) and pulse pressure (PP) in elderly patients with essential hypertension (EH). Methods The parameters of systolic diastolic pressure (SBP), diastolic blood pressure (DBP), PP and echocardiography in 98 patients with essential hypertension were measured and divided into two groups according to the presence or absence of LVH: 42 in non-LVH group, 56 cases. LVH group with heart failure in 26 cases, normal heart function in 30 cases. Results (1) The SBP and PP in LVH group were significantly higher than those in non-LVH group (P <0.01). LVMI and SBP and PP were positively correlated (P <0.01). (2) PP in patients with LVH group with congestive heart failure was higher than that in LVH group (P <0.05). Conclusion PP increased in the development of EH with LVH play a role, PP can be used as an evaluation of antihypertensive drugs can better reduce the target organ damage in patients with an important indicator.