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研究300例系统性红斑狼疮(SLE)患者的死亡率和死亡原因。回顾性分析了1978年1月～2000年7月的300例诊所SLE患者,均符合1982年美国风湿病学院的诊断标准,其中除外药物性狼疮和盘状狼疮病例。病者在确诊SLE后5年内死亡者定为早期死亡,确诊SLE后5年以后死亡者定为晚期死亡。每例均分析其死因,井算出各年龄组SLE患者的标准化死亡比率。 结果SLE患者中的死亡者与存活者相比,可见确诊年龄较高(36.8对28.5岁),SLE患者的平均病程为13年,平均随访时间为8.3
To study the mortality and causes of death in 300 patients with systemic lupus erythematosus (SLE). A retrospective analysis of the January 1978 to July 2000 300 clinics SLE patients, are in line with the 1982 American College of Rheumatology diagnostic criteria, with the exception of drug-induced lupus and cases of discoid lupus. The patient died within 5 years after the diagnosis of SLE as early death, 5 years after the diagnosis of SLE after the death as late death. In each case, the cause of death was analyzed and the standardized death rate for SLE patients was calculated for each age group. Results Compared with survivors, deaths in SLE patients showed a higher age at diagnosis (36.8 vs 28.5 years), an average duration of SLE patients was 13 years and an average follow-up time of 8.3