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甲状腺癌(TC)是发病率最高的内分泌系统肿瘤,其中85%以上为甲状腺乳头状癌(PTC)。桥本甲状腺炎(HT)也称慢性淋巴细胞性甲状腺炎,是最常见的自身免疫性甲状腺炎。PTC与HT之间的关系是近年来的研究热点,因为这一问题涉及到炎症与肿瘤发生的关系这一根本问题,同时,在胃癌和肝癌中,都证实了炎症与肿瘤发生存在确切的关系,然而,在甲状腺癌中,慢性炎症与肿瘤的发生是否也存在类似的关联,仍然没有确切的证据。本文将从4个角度对PTC与HT之间关系的研究进展进行探讨。
Thyroid cancer (TC) is the highest incidence of endocrine system tumors, of which more than 85% of thyroid papillary carcinoma (PTC). Hashimoto’s thyroiditis (HT), also known as chronic lymphocytic thyroiditis, is the most common autoimmune thyroiditis. The relationship between PTC and HT is a hot research topic in recent years because this issue relates to the fundamental problem of the relationship between inflammation and tumorigenesis and at the same time confirms the exact relationship between inflammation and tumorigenesis in gastric cancer and liver cancer However, in thyroid cancer, there is still no clear correlation between chronic inflammation and the occurrence of tumors. This article will discuss the research progress of the relationship between PTC and HT from four aspects.