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药物性急性问质肾炎(Drug-induced AcuteInterstitial Nephritis,D-AIN)是由药物引起的,以肾间质、肾小管的急性炎症为主要表现的综合征。随着抗生素等多种化学药物的广泛临床应用,其发生率日渐增加。D-AIN临床表现可以不典型,因而常有漏诊、误诊。及时诊断,停用致病药物后,D-AIN的肾功能大都可以恢复,而漏、误诊治或迁延成慢性间质肾炎,则可死于肾功能衰竭,提高本病的诊治水平具有重要临床意义。本文概述D-AIN的诊断及治疗。引起D-AIN的药物抗生素是引起D-AIN的主要药物。不同时期临
Drug-induced acute interstitial nephritis (Drug-induced acute interstitial nephritis, D-AIN) is a drug-induced syndrome characterized by acute inflammation of the renal interstitium and renal tubules. With the wide range of clinical applications of antibiotics and other chemicals, the incidence is increasing. D-AIN clinical manifestations can be atypical, which often missed diagnosis, misdiagnosis. Timely diagnosis, disable the pathogenic drugs, D-AIN most of the renal function can be restored, and leakage, misdiagnosis or delay into chronic interstitial nephritis, you can die of renal failure, improve the diagnosis and treatment of the disease has an important clinical significance. This article provides an overview of D-AIN diagnosis and treatment. Drug antibiotics that cause D-AIN are the main drugs that cause D-AIN. Different periods of time